The Park does actively monitor wildlife near roads. Bikers will be held back or shuttled around hazards, i.e. bear on the road.
Leashed dogs are allowed along the road but not allowed on trails or on buses (plan accordingly if bringing Fido).
The Denali Park Road stretches from the park's entrance and into the backcountry of one of America's largest National Parks. With only the first 15 miles of paved road open to passenger cars, most visitors will explore the sights along the road onboard a bus. But if you're in for the trek, it makes a striking journey on two wheels.
The majority of the road is an easy pedal over gravel roads. The road rolls up and down hills on the way into the park. Sable Mountain and Highway Pass are challenging climbs and the only reason I rated this as anything more than "easy," as they are slow grinds in low gear to the summits. There are six campgrounds along the road with Wonder Lake Campground the last before the road turns north to terminate at the Kantishna airstrip.
On the rare day, Denali peak can be visible form Eielson Visitors Center. Many large Alaska mammals can be viewed along the route, including wolves, brown bear, dall sheep and caribou. We saw a Golden Eagle on our trip out, too.